The Synthesized-Hydroxyapatite Powder from Anadara Granosa Shells using Deposition Time Method for Biomedical Applications
DOI:
https://doi.org/10.25077/jif.16.1.88-96.2024Keywords:
Hydroxyapatite, Anadara Granosa shells , XRD , FTIR , SEMAbstract
Hydroxyapatite (HAp) powder, one of the biomaterials derived from natural sources, could be used in biomedical applications. In this research, the synthesized-HAp powder from Anadara Granosa shells as raw materials had a high calcium carbonate content with variations in deposition time using the precipitation method. Variations of deposition time used were 0 (S0), 24 (S24), and 48 (S48) hours. Fourier Transform Infrared (FTIR), X-Ray Diffractions (XRD), and Scanning Electron Microscopy (SEM) were used to investigate the chemical structure, phase analysis, and morphology of the synthesized HAp powder. FTIR results of the S0, S24, and S48 showed that the functional groups , and were formed at variations in the deposition time. The XRD results showed that the smallest of crystallite size of S48 was 26.03 nm, and the crystallinity degree of S24 was 38.74%. The grain dispersity of the synthesized-hydroxyapatite powder from SEM results were uniform, agglomeration, and spherical, irregular shape. The Ca, P, Mg, and Si compositions were shown in the synthesized-hydroxyapatite powder. The deposition time affects the synthesized-Hydroxyapatite (HAp) powder from the Anadara Granosa shell, and it is a potential raw material for biomedical applications.
Downloads
References
Afriani, F., Amelia, R., Hudatwi, M., & Tiandho, Y. (2020). Hydroxyapatite from natural sources: methods and its characteristics. IOP Conference Series: Earth and Environmental Science, 599(1), 12055. DOI: https://doi.org/10.1088/1755-1315/599/1/012055
Almukarrama, & Yusuf, Y. (2019). Development carbonated hydroxyapatite powders from oyster shells (Crassostrea gigas) by sintering time controlling. IOP conference series: materials science and engineering, 546(4), 42001. DOI: https://doi.org/10.1088/1757-899X/546/4/042001
Azis, Y., Jamarun, N., Zultiniar, Z., Arief, S., & Nur, H. (2015). Synthesis of hydroxyapatite by hydrothermal method from cockle shell (Anadara granosa). J Chem Pharm Res, 7(5), 798–804.
Bulut, N., Kaygili, O., Hssain, A. H., Dorozhkin, S. V, Abdelghani, B., Orek, C., Kebiroglu, H., Ates, T., & Kareem, R. O. (2023). Mg-Dopant Effects on Band Structures of Zn-Based Hydroxyapatites: A Theoretical Study. Iranian Journal of Science, 47(5), 1843–1859. DOI: https://doi.org/10.1007/s40995-023-01531-6
Dhanaraj, K., Kumar, C. S., & Suresh, G. (2018). Characterization of calcium oxide (CaO) derived from Perna viridis shell waste through solid state reaction. J. Appl. Sci. Computation, 5(12), 658–665.
Dhanaraj, K., & Suresh, G. (2018). Conversion of waste sea shell (Anadara granosa) into valuable nanohydroxyapatite (nHAp) for biomedical applications. Vacuum, 152, 222–230. DOI: https://doi.org/10.1016/j.vacuum.2018.03.021
Fitriyana, D. F., Ismail, R., Santosa, Y. I., Nugroho, S., Hakim, A. J., & Al Mulqi, M. S. (2019). Hydroxyapatite synthesis from clam shell using hydrothermal method: A review. 2019 International Biomedical Instrumentation and Technology Conference (IBITeC), 1, 7–11. DOI: https://doi.org/10.1109/IBITeC46597.2019.9091722
Ismail, R., Fitriyana, D. F., Santosa, Y. I., Nugroho, S., Hakim, A. J., Al Mulqi, M. S., Jamari, J., & Bayuseno, A. P. (2021). The potential use of green mussel (Perna Viridis) shells for synthetic calcium carbonate polymorphs in biomaterials. Journal of Crystal Growth, 572, 126282. DOI: https://doi.org/10.1016/j.jcrysgro.2021.126282
Kadir, L. A., Permana, D., & Azis, T. (2022). Sintesis dan Karakterisasi Bionano Hidroksiapatit (HAp) Secara Insitu Dengan Metode Hidrotermal. Cokroaminoto Journal of Chemical Science, 4(2), 1–4.
Kareem, R. O., Bulut, N., & Kaygili, O. (2024). Hydroxyapatite biomaterials: a comprehensive review of their properties, structures, medical applications, and fabrication methods. Journal of Chemical Reviews, 6(1), 1–26.
Khoiriyah, M. (2018). Sintesis dan Karakterisasi Bone Graft dari Komposit Hidroksiapatit/Kolagen/Kitosan (HA/Coll/Chi) dengan Metode Ex-Situ sebagai Kandidat Implan TulangSynthesis and Characteritation of Bone Graft from Hydroxyapatite/Collagen/Chitosan (HA/Coll/Chi) Composite By Ex-Situ Method As A Bone Implant Candidates. Unesa Journal of Chemistry, 7(1).
Mtavangu, S. G., Mahene, W., Machunda, R. L., van der Bruggen, B., & Njau, K. N. (2022). Cockle (Anadara granosa) shells-based hydroxyapatite and its potential for defluoridation of drinking water. Results in Engineering, 13, 100379. DOI: https://doi.org/10.1016/j.rineng.2022.100379
Odusote, J. K., Danyuo, Y., Baruwa, A. D., & Azeez, A. A. (2019). Synthesis and characterization of hydroxyapatite from bovine bone for production of dental implants. Journal of applied biomaterials & functional materials, 17(2), 2280800019836829. DOI: https://doi.org/10.1177/2280800019836829
Pazarlioglu, S., & Salman, S. (2019). Effect of lanthanum oxide additive on the sinterability, physical/mechanical, and bioactivity properties of hydroxyapatite-alpha alumina composite. Journal of the Australian Ceramic Society, 55, 1195–1209. DOI: https://doi.org/10.1007/s41779-019-00336-4
Pu’ad, N. A. S. M., Koshy, P., Abdullah, H. Z., Idris, M. I., & Lee, T. C. (2019). Syntheses of hydroxyapatite from natural sources. Heliyon, 5(5). DOI: https://doi.org/10.1016/j.heliyon.2019.e01588
Rizkayanti, Y., & Yusuf, Y. (2018). Effect of temperature on syntesis of hydroxyapatite from cockle shells (Anadara granosa). International Journal of Nanoelectronics and Materials, 11(2018), 43–50.
Saharudin, S. H., Shariffuddin, J. H., & Nordin, N. (2017). Biocomposites from (Anadara granosa) shells waste for bone material applications. IOP Conference Series: Materials Science and Engineering, 257(1), 12061. DOI: https://doi.org/10.1088/1757-899X/257/1/012061
Sari, M., & Yusuf, Y. (2018). Synthesis and characterization of hydroxyapatite based on green mussel shells (perna viridis) with the variation of stirring time using the precipitation method. IOP Conference Series: Materials Science and Engineering, 432, 12046. DOI: https://doi.org/10.1088/1757-899X/432/1/012046
Siswanto, S., Hikmawati, D., Aminatun, A., & Zamawi Ichsan, M. (2019). Hydroxyapatite-Collagen Composite Made from Coral and Chicken Claws for Bone Implant Application. Materials Science Forum, 966, 145–150. DOI: https://doi.org/10.4028/www.scientific.net/MSF.966.145
Srichanachaichok, W., & Pissuwan, D. (2023). Micro/Nano Structural Investigation and Characterization of Mussel Shell Waste in Thailand as a Feasible Bioresource of CaO. Materials, 16(2), 805. DOI: https://doi.org/10.3390/ma16020805
Szterner, P., & Biernat, M. (2022). The synthesis of hydroxyapatite by hydrothermal process with calcium lactate pentahydrate: the effect of reagent concentrations, pH, temperature, and pressure. Bioinorganic Chemistry and Applications, 2022. DOI: https://doi.org/10.1155/2022/3481677
Taji, L. S., Wiyono, D. E., Karisma, A. D., Surono, A., & Ningrum, E. O. (2022). Hydroxyapatite Based Material: Natural Resources, Synthesis Methods, 3D Print Filament Fabrication, and Filament Filler. IPTEK The Journal of Engineering, 8(1), 26–35. DOI: https://doi.org/10.12962/j23378557.v8i1.a12830
Tanzi, M. C., Farè, S., & Candiani, G. (2019). Foundations of biomaterials engineering. Academic Press.
Tjandra, K. C., Novriansyah, R., Limijadi, E. K. S., Kuntjoro, L., & Hendrianingtyas, M. (2023). The effect of green mussel (Perna viridis) shells’ hydroxyapatite application on alkaline phosphatase levels in rabbit femur bone defect. F1000Research, 12, 631. DOI: https://doi.org/10.12688/f1000research.132881.1
Wu, S.-C., Hsu, H.-C., Wang, H.-F., Liou, S.-P., & Ho, W.-F. (2023). Synthesis and Characterization of Nano-Hydroxyapatite Obtained from Eggshell via the Hydrothermal Process and the Precipitation Method. Molecules, 28(13), 4926. DOI: https://doi.org/10.3390/molecules28134926
Zainol, I., Zainurin, M. A. N., Bakar, N. H. A., Jaafar, C. N. A., & Mudhafar, M. (2022). Characterisation of porous hydroxyapatite beads prepared from fish scale for potential bone filler applications. Malaysian Journal of Microscopy, 18(2), 48–57.
Downloads
Published
How to Cite
Issue
Section
Citation Check
License
Copyright (c) 2023 Sunardi Sunardi, Nidha Aulia Qurrata A’yun, Qorinah Wulan Dari, Jamrud Aminuddin, Bilalodin Bilalodin, Budi Praktino, Evi Yulianti, Agung Bambang Budi Utomo, Kartika Sari
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Please find the rights and licenses in JIF (Jurnal Ilmu Fisika).
1. License
The non-commercial use of the article will be governed by the Creative Commons Attribution license as currently displayed on Creative Commons Attribution-NonCommercial 4.0 International License.
2. Author's Warranties
The author warrants that the article is original, written by stated author(s), has not been published before, contains no unlawful statements, does not infringe the rights of others, is subject to copyright that is vested exclusively in the author and free of any third party rights, and that any necessary written permissions to quote from other sources have been obtained by the author(s).
3. User Rights
JIF's spirit is to disseminate articles published are as free as possible. Under the Creative Commons license, JIF permits users to copy, distribute, display, and perform the work for non-commercial purposes only. Users will also need to attribute authors and JIF on distributing works in the journal.
4. Rights of Authors
Authors retain the following rights:
- Copyright, and other proprietary rights relating to the article, such as patent rights,
- The right to use the substance of the article in future own works, including lectures and books,
- The right to reproduce the article for own purposes, provided the copies are not offered for sale,
- The right to self-archive the article.
5. Co-Authorship
If the article was jointly prepared by other authors, the signatory of this form warrants that he/she has been authorized by all co-authors to sign this agreement on their behalf, and agrees to inform his/her co-authors of the terms of this agreement.
6. Termination
This agreement can be terminated by the author or JIF upon two months's notice where the other party has materially breached this agreement and failed to remedy such breach within a month of being given the terminating party's notice requesting such breach to be remedied. No breach or violation of this agreement will cause this agreement or any license granted in it to terminate automatically or affect the definition of JIF.
7. Royalties
This agreement entitles the author to no royalties or other fees. To such extent as legally permissible, the author waives his or her right to collect royalties relative to the article in respect of any use of the article by JIF or its sublicensee.
8. Miscellaneous
JIF will publish the article (or have it published) in the journal if the article's editorial process is successfully completed and JIF or its sublicensee has become obligated to have the article published. JIF may conform the article to a style of punctuation, spelling, capitalization, referencing and usage that it deems appropriate. The author acknowledges that the article may be published so that it will be publicly accessible and such access will be free of charge for the readers.