Dosimetry Verification of Anisotropic Analytical Algorithm (AAA) In Eclipse Treatment Planning System (TPS) Based on Multileaf Collimator Variations


  • Fadillah Ahmad Department of Physics, Faculty of Mathematics and Natural Sciences, Andalas University, Pauh, Padang 25163, Indonesia
  • Afdhal Muttaqin Department of Physics, Faculty of Mathematics and Natural Sciences, Andalas University, Pauh, Padang 25163, Indonesia
  • Dian Fitriyani Department of Physics, Faculty of Mathematics and Natural Sciences, Andalas University, Pauh, Padang 25163, Indonesia
  • Ridwan Ridwan Siemens Healthineers Indonesia, Arkadia Office Park, Jakarta 12520, Indonesia



Anisotropic Analytical Algorithm, Dosimetry Verification, Treatment Planning System, Eclipse, Multileaf Collimator


Dosimetry verification of anisotropic analytical (AAA) algorithms based on variations of the multileaf collimator has been investigated using the Eclipse Treatment Planning System. This study used a 0.6cc ionization chamber farmer detector and Linac Clinical CX variant equipped with TPS Eclipse with AAA. This study used 6 MV energy and 2 Gy dose. The multileaf collimator was varied into six groups with the size (A, B, C, D, E, F) of the irradiation field used 20 cm x 20 cm. The measurement results were a dose deviation value or a dose ratio presentation in each irradiation area. The dose deviation of the multileaf collimator variation was A 0.86% for each group. Group B had 6.8%, Group C had -0.43%, Group D had 0.73%, Group E had 1.11%, and Group F had 0.84%. The mean dose deviation value for all multileaf collimator forms was 1.67%, where this value is within the tolerance value recommended by ICRU, namely 3-5%. The p-value in the Analysis of variance (ANOVA) for the entire group was 0.00. This data shows that there is no effect of variation in the multileaf collimator on the dose given.


Download data is not yet available.


Brezovich, I. A., Wu, X., Popple, R. A., Covington, E., Cardan, R., Shen, S., Fiveash, J., Bredel, M., and Guthrie, B. (2019). Stereotactic radiosurgery with MLC‐defined arcs: Verification of dosimetry, spatial accuracy, and end‐to‐end tests. Journal of applied clinical medical physics 20, 84-98.

Das, I. J., Ding, G. X., and Ahnesjö, A. (2008). Small fields: nonequilibrium radiation dosimetry. Medical physics 35, 206-215.

Fog, L. S., Rasmussen, J. F., Aznar, M., Kjær-Kristoffersen, F., Vogelius, I. R., Engelholm, S. A., and Bangsgaard, J. P. (2011). A closer look at RapidArc® radiosurgery plans using very small fields. Physics in Medicine Biology 56, 1853.

Gagné, I. M., and Zavgorodni, S. (2007). Evaluation of the analytical anisotropic algorithm in an extreme water–lung interface phantom using Monte Carlo dose calculations. Journal of Applied Clinical Medical Physics 8, 33-46.

Götstedt, J., Karlsson Hauer, A., Bäck, and Anna (2015). Development and evaluation of aperture‐based complexity metrics using film and EPID measurements of static MLC openings. Medical physics 42, 3911-3921.

Handayani, M., Milvita, D., Herlinda, S., and Unand, J. J. F. (2016). Verifikasi Ketepatan Hasil Perencanaan Nilai Dosis Radiasi Terhadap Penerimaan Dosis Radiasi Pada Pasien Kanker. Jurnal Fisika Unand 5, 159-165.

Handika, A. D., Tarigan, S. T., Karunia, P. D., Syafi'i, A., Fauzia, A. R., Mar'ie, K., Pontoh, P. A., and Pawiro, S. A. (2020). Audit dosimetri treatment planning system berkas foton pada radioterapi eksternal: A Review. Journal of Medical Physics Biophysics 7, 32-45.

Hasenbalg, F., Neuenschwander, H., Mini, R., and Born, E. (2007). Collapsed cone and analytical anisotropic algorithm dose calculations compared to VMC++ Monte Carlo simulations in clinical cases. In "Journal of Physics: Conference Series", Vol. 74, pp. 021007. IOP Publishing. doi:10.1088/1742-6596/74/1/012007

ICRU (1976). "Determination of absorbed dose in a patient irradiated by beams of X- or gamma-rays in radiotherapy procedures," Washington DC:.

Jursinic, P. A. (1999). Changes in incident photon fluence of 6 and 18 MV x rays caused by blocks and block trays. Medical Physics 26, 2092-2098.

LoSasso, T., Chui, C. S., and Ling, C. C. (1998). Physical and dosimetric aspects of a multileaf collimation system used in the dynamic mode for implementing intensity modulated radiotherapy. Medical physics 25, 1919-1927.

Lu, L., Yembi-Goma, G., Wang, J. Z., Gupta, N., Huang, Z., Lo, S. S., Martin, D., and Mayr, N. (2013). A practical method to evaluate and verify dose calculation algorithms in the treatment planning system of radiation therapy. International Journal of Medical Physics, Clinical Engineering Radiation Oncology 2, 76.

Mu'minah, I. A., La Ode Husein, Z., Pawiro, and A, S. (2015). Verifikasi Dosimetri Perhitungan Berkas Terbuka Perangkat Lunak In-House Treatment Planning System (Tps) Pesawat Teleterapi Cobalt-60. In "Prosiding Seminar Nasional Fisika (E-Journal)", Vol. 4, pp. SNF2015-V-33-38.

Ramdani, R., and Haryanto, F. (2016). Perbandingan Dosis Serap Berkas Foton 16 MV Pada berbagai Jenis Phantom Menggunakan Metode Monte Carlo-EGSnrc. 129-139.

Ridwan, Supriyanto Arjo Pawiro, and Soejoko, D. (2017). Development and evaluation of complexity metric of static MLC openings of linear accelerator. congress of medical physics.

Rutonjski, L., Petrović, B., Baucal, M., Teodorović, M., Čudić, O., Gershkevitsh, E., and Izewska, J. (2012). Dosimetric verification of radiotherapy treatment planning systems in Serbia: national audit. Radiation Oncology 7, 1-8.

Sievinen, J., Ulmer, W., and Kaissl, W. (2005). AAA photon dose calculation model in Eclipse. Palo Alto : Varian Medical Systems 118, 2894.

Suharmono, B. H., Anggraini, I. Y., Hilmaniyya, H., and Astuti, S. D. (2020). Quality Assurance (QA) Dan Quality Control (QC) Pada Instrumen Radioterapi Pesawat LINAC. J Jurnal Biosains Pascasarjana 22, 73-80.

Suharsono (2012). verifikasi dosis radioterapi eksterna metode in vivo pada phantom, Universitas Indonesia, Depok.

Suwandi, Wibowo, W. E., Pawiro, and Ardjo, S. (2016). Simulasi Audit Dosimetri Treatment Planning System Foton Sinar-X 6 Mv Multicenter Radioterapi. In "Prosiding Seminar Nasional Fisika (E-Journal)", Vol. 5, pp. SNF2016-BMP-23-28.

Underwood, R. J. (2013). Small field dose calibrations with gafchromic film. no. May, 73.

Van Esch, A., Tillikainen, L., Pyykkonen, J., Tenhunen, M., Helminen, H., Siljamäki, S., Alakuijala, J., Paiusco, M., Iori, M., and Huyskens, D. P. (2006). Testing of the analytical anisotropic algorithm for photon dose calculation. Medical physics 33, 4130-4148.




How to Cite

Ahmad, F., Muttaqin, A., Fitriyani, D., & Ridwan, R. (2022). Dosimetry Verification of Anisotropic Analytical Algorithm (AAA) In Eclipse Treatment Planning System (TPS) Based on Multileaf Collimator Variations. JURNAL ILMU FISIKA | UNIVERSITAS ANDALAS, 15(1), 48–55.



Research Article

Citation Check